Spiller has been playing through an ankle injury, which has limited his overall productivity and usage in recent weeks. Fred Jackson is dealing with a knee injury, but he expects to play on Sunday.
Spiller is average four yards per carry this season, but only has a total 362 yards rushing and 36 yards receiving. He has only scored a single touchdown in what has been a larger disappointing season for the Bills running back.
Hopefully a week of rest will help him get back to being a productive running back this season.