The Los Angeles Chargers have signed OLB Akheem Mesidor to a four-year, $20,456,392 fully-guaranteed rookie contract, according to Adam Schefter.
| Rd | Pick | Player | Pos. | Note |
| 1 | 22 | Akheem Mesidor | LB | Signed |
| 2 | 63 | Jake Slaughter | C | Signed |
| 4 | 105 | Brenen Thompson | WR | |
| 4 | 117 | Travis Burke | T | Signed |
| 4 | 131 | Genesis Smith | S | Signed |
| 5 | 145 | Nick Barrett | DT | Signed |
| 6 | 202 | Logan Taylor | G | Signed |
| 6 | 206 | Alex Harkey | G | Signed |
Mesidor, 25, signed with West Virginia out of high school and was with the team for two years before transferring to Miami. He was a second-team all conference selection in 2020 and a third-team all conference selection in 2021 at West Virginia. He was a first-team all conference selection in 2025 and second-team all-American at Miami.
He was selected in the first round (22nd overall) in the 2026 draft out of Miami.
Throughout his six-year college career, Mesidor appeared in 65 total games and tallied 208 total tackles, 52.5 tackles for loss, 35.5 sacks, four passes defended and five forced fumbles.
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