Schefter adds in the likely event Guice undergoes surgery, he would be sidelined six to eight weeks.
Guice spent his entire rookie season on injured reserve after tearing his ACL last preseason, but he picked up this injury to his other knee sometime in the last few weeks.
He overcame numerous complications to play in his first regular-season game Sunday. Guice rushed for 18 yards on 10 carries.
Guice, 22, is a former second-round pick of the Redskins back in 2018. He’s currently in the second year of his four-year, $4,541,936 contract that includes a $1,383,224 signing bonus.
During his three-year college career at LSU, Guice rushed for 3,074 yards on 471 carries (6.5 YPC) to go along with 32 receptions for 250 yards receiving 32 total touchdowns over the course 35 games.