49ers HC Kyle Shanahan told reporters on Monday that RB Raheem Mostert will “most likely” be placed on injured reserve with a high ankle sprain, per Nick Wagoner. 
Shanahan added that C Ben Garland is also expected to join Mostert on injured reserve.
It’s worth mentioning that the NFL changed the rules regarding injured reserve for the 2020 season and players can return from the list after just three games.
Mostert missed some time earlier in the season with an MCL sprain.
Mostert, 28, wound up signing on with the Eagles as an undrafted free agent out of Purdue back in 2015. He had brief stints with the Dolphins, Ravens, Browns, Jets and Bears before signing on to the 49ers’ practice squad in 2016.
The 49ers brought Mostert back on a one-year exclusive rights contract in 2018 before tendering him a restricted offer in 2019. He later signed a three-year, $8.7 million extension with San Francisco.
However, the two parties agreed to a restructured contract this summer.
In 2020, Mostert has appeared in four games for the 49ers and rushed for 303 yards on 51 carries (5.9 YPC) to go along with 11 receptions for 150 yards and two touchdowns.
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Everytime we win, it seems like we lose more.
But at least your Coach plays the best situational football by using the talents of players to their best! Nagy fails to understand that different players play better in given situations….he only plays the players he feels like play best in his scheme and forgets about talent in situational football!