Barkley tore his ACL in Week 2 last season and suffered additional damage to his knee, so it’s not surprising he will open camp on the list.
Barkley will still count against the Giants’ 90-man roster and can be activated at any time.
Barkley, 24, was the second-overall pick in the 2018 NFL Draft. He’s entering the fourth year of a four-year, $31.19 million rookie deal with the Giants that included a $20.767 million signing bonus.
The Giants picked up Barkley’s fifth-year option worth $7.22 million fully guaranteed for the 2022 season this past April.
In 2020, Barkley was limited to two games with a knee injury, tallying 34 yards on 19 carries and no touchdowns. He also accrued 60 yards on six total catches.