The two are the latest starters for Detroit to be placed on injured reserve before the end of the season.
Daniels was a big-ticket free agent signing after Green Bay made him a cap casualty in training camp. However, he was never able to get off the ground in his first year with the Lions.
Both Daniels and Wiggins are set to be free agents at the end of the season.
Daniels, 30, is a former fourth-round pick of the Packers back in 2012. He was entering the final year of his five-year, $41.66 million contract and set to make a base salary of $7.6 million for the 2019 season when the Packers released him.
Daniels signed a one-year, $9.1 million deal with the Lions for the 2019 season.
In 2019, Daniels appeared in nine games for the Lions and recorded 10 tackles and one sack.
Wiggins, 31, wound up signing on with the 49ers as an undrafted free agent out of Fresno State back in 2011. He lasted just a few months with the team before he was signed to the Ravens’ practice squad at the start of the 2011 season.
Wiggins would later return to San Francisco during his rookie year before ending up with the Chargers at the start of the 2013 season. He spent five years with the Chargers before signing a two-year deal with the Lions in 2018.
In 2019, Wiggins has appeared in 14 games for the Lions with three starts and is rated by Pro Football Focus as the No. 37 guard out of 78 qualifying players.